Mali international midfielder Yves Bissouma is suspended while experienced campaigner Dale Stephens this week completed a £1m switch to Burnley.
Scroll down and click through to see how we think Graham Potter could tweak his line-up against United.
5. Tariq Lamptey
Tipped to recover from a bruising encounter at Newcastle and I hope he does. Albion will need his skill, pace and energy down the right flank
6. Steven Alzate
Started the first two matches of the Premier League campaign in his favoured central midfield position. With Bissouma suspended, Stephens departed and Propper getting back to full fitness, Alzate looks set for a key role once more
7. Jayson Molumby
With Bissouma out and Propper perhaps not yet at full tilt, Molumby could be line for a Premier League debut. Will be a bold decision from Potter but the ROI international impressed last year on loan at Millwall and adds energy and competitiveness in midfield.
8. Leo Trossard
Will likely get the nod as the main attacking midfielder ahead of Lallana who is almost back to full fitness after cramping up against Chelsea. Trossard in this role also allows Connolly and Maupay to do their business a high energy attacking duo