Emergency services were called this morning (Friday, January 27) following a report that a pedestrian had collided with a car in Victoria Drive, Eastbourne.
Police said the 69-year-old woman, was flown to the Royal Sussex County Hospital in Brighton by air ambulance having suffered a significant head injury.
She remains in a serious condition following the incident, which occurred just after 10am.
The driver of the blue Vauxhall Zafira, a 46-year-old woman, also local to the area, was uninjured.
Sergeant Dan Pitcher, from the roads policing unit, said: “We are asking anyone who was in the area at the time and may have seen what happened to get in touch. Anyone with information can email firstname.lastname@example.org or call 101 quoting Operation Tristar.”
Victoria Drive remained closed while police and ambulance dealt with the incident but re-opened just after 1.15pm.
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