The Andy Knight memorial Trophy match will be held on Sunday, August 26 at the Oval (kick-off 5pm).
All proceeds will go to the Polegate Chrildren with Cancer Fund while funds raised from the tombola will be sent to the Alfriston Pre-School.
Knight died in 2008 after he was diagnosed with lung cancer at the age of 44.
Andy was a respected referee and a passionate Arsenal fan. He was also the manager of Alfriston Pre-School.
It is the fourth year of the event and last year it raised £2,700 for the Polegate Children with Cancer Fund.