It forms part of the national deep clean of hospitals announced by Health Secretary Alan Johnson in November last year.
The Trust has welcomed the additional national deep clean funding which will enhance its own ongoing campaign to reduce Clostridium difficile, MRSA and other hospital acquired infections.
Dr Umasankar, consultant microbiologist and director of infection control, said, "Infection control and patient safety is a priority for this Trust.
"We have made significant progress on reducing infections showing a year-on-year reduction in the number of hospital cases.
"However, we are not complacent. It is important for everyone in the Trust and the community to help reduce infection rates by understanding the importance of implementing good infection prevention and control at all times.
"This enhanced deep cleaning programme will decontaminate our hospitals."
The deep clean programme will be completed by March 31 and involves a considerable amount of work across the hospital's 74 wards and clinical units.
Every ward will be thoroughly cleaned including bed frames, lockers, behind radiators, air vents, lights, shelves, corridors, bathrooms, floors, computers, telephones, kitchens, curtains, linen skips, trolleys, fans and work surfaces.
Along with traditional disinfectants other methods such as hydrogen peroxide vaporisation and steam cleaning will be used where appropriate.
A specialist contractor will use the latest equipment to disperse hydrogen peroxide vapours throughout the wards to decontaminate every surface and area of any germs likely to cause infection.
Tina Lloyd, lead nurse for infection control, said, "We apologise to patients and their families who may be inconvenienced by being moved around while this deep clean is undertaken.
"We shall take great care to do the cleaning as quickly, efficiently and safely as possible to minimise disruption without compromising the aim of the exercise — to reach the highest possible standards of cleanliness."